Scale-up of Processes and Products

Process scale-up is about developing new processes for existing products. This scale-up is applied in bulk chemicals and other industry branches with large capacity processes. Product scale-up is about developing new products to be produced in existing processes. This...

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Learning Points Course Process Scale-up

I lead a course on Process Scale-up last May. I always learn new aspects while giving this course, I will share with you 4 learning points I took away from this course: This time I learned from the course participants that a company who lacked process concept design...

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CHISA 2022 Prague – takeway messages

Co-operation between industrial engineers, researchers, and government is needed to fulfil world-wide Sustainable Development Goals, was the main take-away message from the CHISA conference, Prague, 22-25 August 2022. Professor David Rivas gave a plenary lecture...

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Vocabulary of Process Intensification Field

I review papers on the subject of Process Intensification (PI). Often the researchers struggle with the proper use of terms. I also give a course on PI for industrial chemical engineering practitioners. In some cases, participants struggle with the meaning of terms...

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Ten Rules for Successful Scale-up

Here are the ten rules for successful scale-up of processes to industrial production scale. The rules have been derived from literature on scale-up and validated by industrial scale implementations. The rules are applicable to continuous and batch operated processes...

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Affinity Separations

By affinity separation one component is selectively separated from a soup of components. It is very attractive for separations in pharmaceuticals, food, and drinking water industry branches. Latest results from industry partners and academia were presented at the...

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How to develop processes faster

Developing a new process typically takes 6 years. It even can take decades. However, it can be faster and still have a successful in start-up. Here are four key elements for a faster and still reliable scale-up. Follow all critical success factors for development and...

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Affinity Separation

Seminar: NL GUTS Topic: Affinity Separation Date/time: Wednesday October 20th 2021 / 10.00h -17.30h Location: BODEC, Scheepsboulevard 3, 5705 KZ Helmond   News item   By affinity separation one component is selectively separated from a component soup. It is...

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Feasibility innovation stage advantages

Industrial process innovation nowadays is along innovation stages. Major innovation stages used are concept, development, and implementation. This is a relatively new stage in between concept and development, called feasibility stage. The purpose of the feasibility...

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Vocabulary Sustainable Design of processes and products

"Sustainable development is not a fixed state of harmony, but a process of change in which the exploitation of resources, the direction of investments, the orientation of technological development and institutional change are made consistent with future as well as...

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Vocabulary Process Scale-up

I give courses on process scale-up. In these courses always questions arise about the meaning of terms. Here are some definitions of terms and also alternative definitions. The general advice is always to ask further explanation if terms below are used. Scale-up is...

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Project auditing experiences of Jan Harmsen

Here is some information on three of my technical audit experiences for companies. These three audits cover the innovation trajectory from idea to commercial scale implementation. One audit was on a project in the early concept stage, one audit was on a project in the...

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Industrial Process Scale-up Courses are hot

Since August 2020 I have given 2 scale-up courses for in total over 60 participants, all from industry. I  also received requests from clients, via Symmetric, to provide inhouse scale-up courses. For the third course, due 24-26 November 2021 participant already write...

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